斯坦福大学(生物化学视频课程)# j& H+ @( \; ]1 F6 C
BIO 生物化学/ U+ y% h" B3 i" w4 b' z, a2 C+ Z, J
Biochemistry
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课时学分:3 cr. $ T9 s- y5 O3 }' ^: I
课程介绍: Metabolism. Glycolysis, gluconeogenesis, citric acid cycle, oxidative: q3 a- y( \& S' M
phosphorylation, pentose phosphate pathway, glycogen metabolism, fatty acid metabolism, protein degradation and amino acid catabolism, protein translation and amino acid biosynthesis, nucleotide biosynthesis, DNA replication recombination and repair, lipid and steroid biosynthesis. Medical consequences of impaired metabolism. Therapeutic intervention of metabolism.' U3 p$ F; X0 j
课前必备: [BIO 有机化学],[BIO 化合物结构与活性]
2 g, N! D/ C+ P9 t5 D4 a/ V/ X任课教授: Chaitan Khosla2 A. ?6 g2 k; G$ ^8 j" x
- w+ o8 h+ @: N/ x4 X0 Y; LChaitan Khosla
% C, x5 @2 q# U5 V2 t5 m2 @Title: Stanford Professor; Wells H. Rauser and Harold M. Petiprin Professorship in the School of Engineering
" m9 M d# A% z) P* u5 m' CDepartment(s): Chemical Engineering, Biochemistry by courtesy, Chemical Engineering, Chemistry, Stanford University
5 L8 ^; w, U: E3 S7 `Affiliation(s): Chair, Chemical Engineering
7 h" j1 {2 Y- ], U& x9 D. d% WResearch Statement
4 d0 s. f# ?6 w0 JResearch interests in Khosla's laboratory lie at the interface of enzyme chemistry and medicine. For the past several years the group has investigated the catalytic mechanisms of polydetide synthases, with the concomitant goal of harnessing their programmable chemistry for the biosynthesis of new, pharmaceutically relevant natural K2 h p3 A! @+ Q7 j
products. Recently, the group has also undertaken a new project aimed at understanding and modulating the molecular basis of Celiac Disease, a genetically inherited human autoimmune disorder.; S' `2 d' f% i' S; P3 e2 B* A
配套教材: Biochemistry, 5th edition. J.M. Berg, J.L. Tymoczko, L. Stryer (W.H. Freeman)7 ~4 l2 P0 ^) F. q. K, B
Other Useful Materials:
# n: R S g2 Q. Y2 _A Clinical Companion to Accompany Biochemistry, 5th edition. K. Saltsman, J.Berg, G. Tomaselli (W.H. Freeman)
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